Lisinopril/Hydrochlorothiazide – Oral, Prinzide, Zestoretic

Warning Medication Uses How To Use Side Effects Precautions Drug Interactions Overdose Notes Missed Dose Storage WARNING: This drug can cause serious harm to an unborn baby if used during pregnancy. It is important to prevent pregnancy while taking this medication. Consult your doctor for more details and to discuss reliable forms of birth control. If you are planning pregnancy, become pregnant, or think you may be pregnant, contact your doctor immediately. USES: This medication treats high blood pressure (hypertension). Lowering blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: lisinopril and hydrochlorothiazide. Lisinopril is an ACE inhibitor that relaxes blood vessels. Hydrochlorothiazide is a diuretic that helps eliminate extra salt and water. This product is used when one drug is not controlling blood pressure. Your doctor may direct you to take the individual medications first and then switch to this combination product. Do not continue taking the individual medications after starting this medication.OTHER This section contains uses of this drug that may be prescribed by your health care professional. Use this drug for a condition listed in this section only if prescribed by your health care professional.This medication may also treat heart failure. HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before starting this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. If this medication causes you to urinate more frequently, take it at least 4 hours before bedtime to prevent waking up to urinate.If you take drugs to lower your cholesterol, take lisinopril/hydrochlorothiazide at least 4 hours before or after those medications.The dosage is based on your medical condition and response. Use this medication regularly to get the most benefit. Take it at the same time each day. Continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.Tell your doctor if your condition does not improve or worsens.SIDE EFFECTS: Dizziness, lightheadedness, tiredness, or headache may occur as your body adjusts to the medication. Dry cough may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: fainting, symptoms of high potassium blood level (muscle weakness, slow/irregular heartbeat), signs of infection (fever, chills, persistent sore throat), unusual change in urine amount, decrease in vision, eye pain.This product may cause a loss of too much body water and salt/minerals. Tell your doctor right away if you have any symptoms of dehydration or mineral loss, including: extreme thirst, very dry mouth, muscle cramps/weakness, fast/slow/irregular heartbeat, confusion, decreased urination.This drug may rarely cause serious liver problems. Tell your doctor right away if you notice any of these rare but serious side effects: dark urine, persistent nausea/vomiting, severe stomach/abdominal pain, yellowing eyes/skin.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to lisinopril or hydrochlorothiazide, or other ACE inhibitors, or if you have any other allergies. This product may contain inactive ingredients that can cause allergic reactions. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: history of an allergic reaction that included swelling of the face/lips/tongue/throat, blood filtering procedures, desensitizing treatment for bee/wasp sting allergy, gout, kidney disease, liver disease, collagen vascular disease.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can do so safely. Limit alcoholic beverages.Severe sweating, diarrhea, or vomiting can increase the risk of lightheadedness or dehydration. Report prolonged diarrhea or vomiting to your doctor. To prevent dehydration, drink plenty of fluids unless your doctor directs you otherwise.If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet.This medication may make you more sensitive to the sun. Avoid prolonged sun exposure and use sunscreen and protective clothing when outdoors.This product may affect your potassium levels. Consult your doctor before using potassium supplements or salt substitutes.Before surgery, tell your doctor or dentist about all the products you use.Older adults may be more sensitive to the side effects of this drug, especially dizziness and unusual change in urine amount.This medication is not recommended for use during pregnancy due to the risk for harm to an unborn baby. Consult your doctor for more details.It is unknown if lisinopril passes into breast milk. Hydrochlorothiazide passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

QUESTION

DRUG INTERACTIONS: See How to Use and Precautions sections.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.Some products that may interact with this drug include: aliskiren, lithium, drugs that may increase potassium levels, birth control pills containing drospirenone.Check the labels on all your medicines because they may contain ingredients that could increase your blood pressure or worsen your heart failure. Ask your pharmacist for more details.This medication may interfere with certain laboratory tests, possibly causing false results. Make sure laboratory personnel and all your doctors know you use this drug. OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting. NOTES: Do not share this medication with others.Lifestyle changes such as stress reduction, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Laboratory and/or medical tests should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.Check your blood pressure regularly while taking this medication. Learn how to monitor your own blood pressure and share the results with your doctor. MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Information last revised March 2014. Copyright(c) 2014 First Databank, Inc.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.CONDITIONS OF USE: The information in this database is intended to supplement the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet, or commencing or discontinuing any course of treatment.CONDITIONS OF USE: The information in this database is intended to supplement the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet, or commencing or discontinuing any course of treatment.