Iron/Folic Acid/Vitamin/Mineral

Iron/Folic Acid/Vitamin/Mineral is a combination of micronutrients, including multivitamins, iron, and minerals, that is used to supplement natural deficiencies in adults. It is used to treat iron deficiency anemia that responds to oral iron therapy and for folic acid supplementation in patients on kidney dialysis. Iron/Folic Acid/Vitamin/Mineral oral tablets contain iron, B group vitamins (including B9, or folic acid, and B12, or cobalamin), and minerals such as calcium and sodium.

Iron is an important component of hemoglobin, the protein in red blood cells that delivers oxygen to all tissues, and myoglobin, the muscle protein that stores and releases oxygen when saturation drops. In addition to oxygen transport and storage, iron is essential for various cellular processes, enzyme and hormone synthesis, DNA synthesis and repair, electron transport, and energy metabolism.

Folic acid is the synthetic form of folate, a natural vitamin B9 found in food, and is commonly used in supplements. Folate is a water-soluble vitamin that is crucial for various cellular functions, including the metabolism of amino acids, DNA and RNA synthesis, and the synthesis and growth of all cells, especially red blood cells.

Vitamin B12 is another essential micronutrient that is necessary for normal cell reproduction, red blood cell formation, DNA synthesis, and myelin synthesis, which is a substance that protects nerve fibers and enables normal nerve signal transmission. Active absorption of vitamin B12 from the gastrointestinal tract requires intrinsic factor, a glycoprotein secreted by the gastric mucous layer.

Iron/Folic Acid/Vitamin/Mineral supplementation is used to treat:

• Iron deficiency anemia responsive to oral iron therapy, including hypochromic anemia associated with pregnancy, chronic and/or acute blood loss, metabolic disease, post-surgical recovery, and dietary needs.

Warnings

• Do not take Iron/Folic Acid/Vitamin/Mineral if you are hypersensitive to any of its components.
• Do not administer Iron/Folic Acid/Vitamin/Mineral to anyone under the age of 18.
• The underlying cause and type of anemia should be determined before starting supplementation. If possible, the underlying cause should be treated.
• The Iron/Folic Acid/Vitamin/Mineral treatment regimen contains succinic acid, an alpha, omega acid. Ingesting more than 3g of omega fatty acids per day can have anti-clotting effects and increase bleeding time and international normalized ratio (INR). Avoid using concurrently with anticoagulants, as it can increase the risk of bleeding. Also, avoid use in patients with bleeding disorders.

QUESTION

What are the side effects of Iron/Folic Acid/Vitamin/Mineral?

Common side effects of Iron/Folic Acid/Vitamin/Mineral include:

• Hypersensitivity
• Allergic sensitization
• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Dark stools
• Constipation

If you experience any of the following symptoms or serious side effects while using this drug, seek medical attention immediately:

• Serious heart symptoms, such as fast or pounding heartbeats, fluttering in the chest, shortness of breath, or sudden dizziness
• Severe headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady
• Severe nervous system reaction, including very stiff muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, and feeling like you might pass out
• Serious eye symptoms, such as blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights

This is not a complete list of all side effects or adverse reactions that may occur from the use of this drug. Contact your doctor for medical advice about serious side effects or adverse reactions. You may also report side effects or health problems to the FDA at 1-800-FDA-1088.

What are the dosages of Iron/Folic Acid/Vitamin/Mineral?

Irospan 24/6 tablet

• Regimen consists of 24 tablets of iron, vitamins, and minerals PLUS 6 tablets of succinic acid with vitamins and minerals
• Iron/multivitamin/mineral tablet (days 1-24): sodium ascorbate 100 mg, calcium formate 155 mg, thiamine 5 mg, riboflavin 5 mg, niacin 25 mg, pyridoxine 30 mg, folic acid 1 mg, biotin 300 mcg, calcium pantothenate 300 mcg, ferrous bisglycinate 65 mg, iron dextran 65 mg
• Succinic acid/multivitamin/mineral tablet (days 25-30): sodium ascorbate 100 mg, calcium carbonate 100 mg, thiamine 5 mg, riboflavin 5 mg, niacin 25 mg, pyridoxine 30 mg, folic acid 1 mg, cyanocobalamin 10 mcg, biotin 300 mcg, calcium pantothenate 7 mg, succinic acid 150 mg

Nephron FA

• Tablet: iron (ferrous cation) 66 mg, ascorbic acid 40 mg, niacinamide 20 mg, pyridoxine 10 mg, pantothenic acid 10 mg, riboflavin 1.7 mg, thiamine 1.5 mg, folic acid 1 mg, biotin 0.3 mg, and cobalamin 0.006 mg

Corvite FE

• Tablet: calcium ascorbate 160 mg, calcium threonate 5 mg, ferrous carbonyl (elemental iron) 150 mg, cholecalciferol 1000 IU, pyridoxine 10 mg, folic acid 1 mg, cyanocobalamin 15 mcg, magnesium malate 15 mg, and zinc glycinate 25 mg

Adult:

Iron Deficiency Anemia

• Indicated for the treatment of anemias that respond to oral iron therapy, including hypochromic anemia associated with pregnancy, chronic and/or acute blood loss, metabolic disease, post-surgical recovery, and bleeding diathesis
• Irospan 24/6: 1 iron/multivitamin/mineral tablet orally once daily on days 1-24, and then 1 succinic acid/multivitamin/mineral tablet orally once daily on days 25-30; repeat cycle
• Corvite FE: 1 tablet orally once daily

Kidney Dialysis Supplement

• Indicated for folic acid supplementation for patients on kidney dialysis
• Nephron FA: 1 tablet orally once daily on an empty stomach

Pediatric:

• Safety and efficacy have not been established

Overdose

• The initial symptoms of acute iron overdose may include abdominal pain, nausea, vomiting, diarrhea, tarry stools (melena), blood in vomit (hematemesis), low blood pressure (hypotension), rapid heart rate (tachycardia), excessive acidity of body fluids (metabolic acidosis), high blood sugar (hyperglycemia), dehydration, drowsiness, pallor, bluish skin (cyanosis), lassitude, seizures, shock, and coma.
• Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years of age.
• Iron/Folic Acid/Vitamin/Mineral overdose may be treated with symptomatic and supportive care as required.

What drugs interact with Iron/Folic Acid/Vitamin/Mineral?

Inform your doctor of all medications you are currently taking to identify any potential drug interactions. Do not start, stop, or change the dosage of any medication without your doctor’s recommendation.

• Iron/Folic Acid/Vitamin/Mineral has no known severe interactions with other drugs.
• Serious interactions of Iron/Folic Acid/Vitamin/Mineral include pafolacianine, omadacycline, and sarecycline.

The above list does not include all possible interactions or adverse effects. For more information on drug interactions, visit the RxList Drug Interaction Checker.

Always inform your doctor, pharmacist, or healthcare provider about all prescription and over-the-counter medications you are using, including the dosage of each. Keep a list of this information. If you have any questions about the medication, consult your doctor or healthcare provider.

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Pregnancy and breastfeeding

• Micronutrient deficiency is common in pregnant and breastfeeding women due to their increased nutrient requirements, which can be challenging to meet through diet alone.
• Nutrient supplementation is recommended for women before conception, during pregnancy, and while breastfeeding to promote the health of both the mother and the fetus/baby.
• Obtaining necessary micronutrients from dietary sources is the preferred method. Iron/Folic Acid/Vitamin/Mineral is recommended for use in pregnant and breastfeeding women to prevent deficiencies of iron, folic acid, and other micronutrients, and to reduce the risk of maternal anemia and low birth weight in newborns.
• Pregnant and breastfeeding women should consult their healthcare providers to determine the right product for their individual needs.

What else should I know about Iron/Folic Acid/Vitamin/Mineral?

• Take Iron/Folic Acid/Vitamin/Mineral exactly as directed and do not exceed recommended dosages.
• If you are taking other medications, consult your physician before taking Iron/Folic Acid/Vitamin/Mineral.
• Discontinue use and consult your physician if you experience any adverse effects.
• Store Iron/Folic Acid/Vitamin/Mineral safely out of reach of children. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years of age.
• In case of overdose, seek immediate medical help or contact Poison Control.

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Summary

Iron/Folic Acid/Vitamin/Mineral is a combination of micronutrients, including multivitamins, iron, and minerals, used to supplement natural deficiencies in adults. It is used to treat iron deficiency anemia that responds to oral iron therapy and for folic acid supplementation in patients on kidney dialysis. Common side effects of Iron/Folic Acid/Vitamin/Mineral include hypersensitivity, allergic sensitization, nausea, vomiting, abdominal pain, diarrhea, dark stools, and constipation.