Leuprolide Monthly (3.75 mg) – Injection, Lupron Depot

Medication Uses: Leuprolide treats uterus disorders in women such as endometriosis and fibroids. It reduces symptoms like pelvic pain, heavy menstrual periods, and abdominal bloating. Leuprolide also shrinks abnormal uterine tissue that causes these symptoms. It is usually given with iron to improve anemia caused by vaginal bleeding from fibroids. Leuprolide stops early puberty in children by delaying sexual development and slowing down early bone growth to increase the chance of reaching normal adult height. It works by decreasing the amount of sex hormones that the body makes.

Side Effects: Common side effects include hot flashes, increased sweating, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal discomfort/dryness, abnormal vaginal bleeding in girls, ankle/foot swelling, dizziness, and mild pain/bruising at the injection site. Serious side effects may include mental/mood changes, bone pain, easily broken bones, and seizures. Contact a healthcare professional immediately if you experience severe headache, severe mental/mood changes, vision changes, severe vomiting, or fainting. Allergic reactions to this drug are rare, but seek medical help if you notice symptoms of a serious allergic reaction such as rash, swelling, severe dizziness, or trouble breathing.

Precautions: Inform your doctor or pharmacist of any allergies to leuprolide or other ingredients in the medication. Consult your healthcare professional before using this drug if you have vaginal bleeding of unknown cause, high blood fat levels, depression, osteoporosis, or any risk factors for osteoporosis. Leuprolide may cause dizziness, so avoid activities that require alertness until you know how the drug affects you. This medication should not be used during pregnancy and breastfeeding is not recommended.

Drug Interactions: Inform your doctor or pharmacist about all prescription and nonprescription/herbal products you are using. Keep a list of all your medications and share it with your healthcare professional.

Overdose: If overdose is suspected, contact a poison control center or emergency room immediately.

Notes: Do not share this medication with others. Regular laboratory and/or medical tests should be performed to monitor your progress and check for side effects.

Missed Dose: Contact your doctor promptly if you miss a dose or if you miss 2 or more doses in a row.

Storage: Store at room temperature away from moisture. Once mixed, use the medication immediately. Keep all medicines away from children and pets. Properly discard this product when it is expired or no longer needed.

Report Problems to the Food and Drug Administration: Report any negative side effects of prescription drugs to the FDA.

Conditions of Use: This information is intended to supplement the expertise and judgment of healthcare professionals. Consult a healthcare professional before taking any drug or changing any diet or treatment.