Eletriptan – Oral, Relpax

Medication Uses How To Use Side Effects Precautions Drug Interactions Overdose Notes Missed Dose Storage USES: Eletriptan is used to treat migraines. It helps relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Eletriptan belongs to a class of drugs known as triptans. It affects serotonin, a natural substance that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain. Eletriptan does not prevent future migraines or lessen the frequency of migraine attacks. HOW TO USE: Read the Patient Information Leaflet available from your pharmacist before you start using eletriptan and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, at the first sign of a migraine. The dosage is based on your medical condition and response to treatment. If there is no improvement in your symptoms, do not take more doses of this medication before talking to your doctor. If your symptoms are only partly relieved, or if your headache comes back, you may take another dose two hours after the first dose. For the US product, do not take more than 80 milligrams in a 24-hour period. For the Canadian product, the manufacturer recommends a maximum of 40 milligrams in a 24-hour period. If you have a higher risk for heart problems, your doctor may perform a heart exam before you start taking eletriptan. He/she may also direct you to take your first dose of this medication in the office/clinic to monitor for serious side effects (such as chest pain). Talk to your doctor for details. Overusing drugs to treat sudden migraine attacks can lead to worsening of headache or rebound headache. Therefore, do not use this medication more often or for longer than prescribed. Tell your doctor if you need to use this medication more often, if the medication is not working as well, or if you have more frequent or worse headaches. Your doctor may need to change your medication and/or add another medication to help prevent headaches. SIDE EFFECTS: Nausea, feelings of tingling/numbness, weakness, tiredness, drowsiness, or dizziness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: blue fingers/toes/nails, cold hands/feet. Chest/jaw/neck tightness can commonly occur soon after using eletriptan. Only rarely are these signs of a serious condition. However, you may not be able to tell it apart from a serious reaction due to a lack of blood flow to the heart, brain, or other parts of the body. Get medical help right away if you have any very serious side effects, including: chest pain, jaw/left arm pain, fainting, fast/irregular/pounding heartbeat, vision changes, weakness on one side of the body, confusion, slurred speech, sudden or severe stomach/abdominal pain, bloody diarrhea, change in the amount of urine. This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA. In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada. PRECAUTIONS: Before taking eletriptan, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems, certain types of headaches, heart problems, liver disease, seizure, stroke or "mini-stroke". Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions. This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Before having surgery, tell your doctor or dentist about all the products you use. The risk of heart disease and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Consult your doctor before breast-feeding. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Avoid taking certain medications that can affect the removal of eletriptan from your body within 72 hours of taking eletriptan. Examples include cobicistat, nefazodone, azole antifungals, macrolide antibiotics, certain hepatitis C virus protease inhibitors, HIV protease inhibitors, among others. If you also take any ergotamine medication or other "triptan" drugs, separate your eletriptan dose at least 24 hours apart from your dose of these other medications to lessen the chance of serious side effects. The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/"ecstasy," St. John’s wort, certain antidepressants, among others.

QUESTION

OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center. Canada residents can call a provincial poison control center. NOTES: Do not share this medication with others. Certain foods, beverages, or food additives as well as lifestyle patterns such as irregular eating/sleeping habits or stress may bring on a migraine headache. Avoiding these "triggers" may help lessen migraine attacks. Consult your doctor for more details. Laboratory and/or medical tests may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. MISSED DOSE: Not applicable. STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Information last revised January 2014. Copyright(c) 2014 First Databank, Inc.

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CONDITIONS OF USE: The information in this database is intended to supplement the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.