Ycanth

Ycanth is a prescription topical medication for molluscum contagiosum in adult and pediatric patients 2 years and older.

Warnings

• Life-threatening toxicities can occur if taken orally. Avoid contact with treated area, including oral contact, after treatment. Ocular toxicity can occur if Ycanth comes in contact with eyes. If Ycanth gets in your eyes, flush with water for at least 15 minutes.
• Reactions at application site may include vesiculation, pruritus, pain, discoloration, and erythema. Avoid application near eyes, mucosal tissue, and healthy skin. If Ycanth contacts unintended surface or healthy skin, immediately remove. If severe local skin reactions occur, remove prior to 24 hours after treatment.
• Ycanth is flammable, even after drying. Avoid fire, flame, or smoking near lesion(s) during and after treatment until removed.

Side Effects of Ycanth

• Serious side effects if swallowed or comes into contact with mouth or eyes.

• Can cause life-threatening reactions or death if swallowed, including kidney failure, blisters and severe damage to stomach and intestine, blood clotting problems, seizures, and certain type of paralysis. If ingested, contact Poison Control Center (1-800-222-1222) or go to the nearest hospital emergency room immediately.
• ulcers or small holes in eyes
• scarring
• redness
• irritation
• severe eye pain
• permanent eye injury, including blindness. If Ycanth accidentally gets into your eyes, flush with water for at least 15 minutes and get medical help immediately.
• small fluid-filled or non-fluid filled raised blisters on or around treated area(s)
• pain
• itching
• scabs
• redness
• lightening or darkening of skin in treated area(s)
• dry skin at treated area(s)
• swelling on or near treated area(s)
• breakdown of outer layer of skin at treated area(s). If you develop severe blistering, severe pain, or other severe reactions at treated areas of skin, wash Ycanth off your skin sooner than 24 hours and call your healthcare provider.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Verrica Pharmaceuticals Inc. at 1-877-837-7422.

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Dosage for Ycanth

Important Administration Instructions

• All healthcare professionals should receive instruction and training prior to preparation and administration of Ycanth.
• Ycanth is for topical use only.
• Ycanth is not for oral, mucosal, or ophthalmic use. Avoid contact with treated area, including oral contact, after Ycanth treatment. Do not apply Ycanth near eyes.
• If Ycanth contacts unintended surface, including healthy skin, immediately remove by wiping with a cotton swab or gauze. Avoid other topical products on treated areas until 24 hours after Ycanth treatment or until washing.
• Avoid fire, flame, or smoking near lesion(s) during treatment.

Dosage and Administration Overview

• Regarding Ycanth dosage and administration:

• Use nitrile or vinyl gloves and eye protection during preparation and administration.
• Apply topically as a single application to cover each lesion. Use no more than two Ycanth applicators during a single treatment session.
• Remove with soap and water 24 hours after treatment. Administer Ycanth every 3 weeks as needed.
• Do not cover treated lesions with bandages.
• If severe blistering, severe pain, or other severe adverse reactions occur, remove Ycanth with soap and water prior to 24 hours after treatment.
• Do not reuse the applicator. The applicator is for a single treatment session only.
• Do not attempt to use a clogged applicator. Do not cut or modify the applicator; doing so could reduce dispensing control.
• Do not remove the applicator cap before breaking the glass ampule.
• If any damage or leaks are observed on the applicator or break tool, discard applicators in a sharps container and handle in accordance with accepted medical practice and applicable law. The Ycanth Break Tool should be managed as solid waste and placed in plastic recycling containers or the general trash.

Other Administration Information

On the day of treatment, do not apply topical steroids, creams, lotions, or sunscreen to areas with molluscum bumps.

After your healthcare provider applies Ycanth to your molluscum bumps:

• Allow Ycanth to dry completely before leaving your healthcare provider’s office or clinic (up to 5 minutes).
• Do not touch treated areas for 24 hours or until washing.
• Do not allow treated areas of your skin to come into contact with your mouth, nose, genital areas, or your eyes for 24 hours or until washing.
• Do not allow children to lick or bite treated areas. Ycanth contains a bittering agent to discourage young children from putting it in their mouths.
• Do not apply topical steroids, creams, lotions, or sunscreen to treated areas for 24 hours after treatment or until you wash Ycanth off your skin.
• Do not cover treated areas with bandages.
• Ycanth contains a violet-colored dye. You may temporarily see the violet color on treated areas of your skin.
• You may take over-the-counter pain relief medicines as needed.
• Wash treated skin area with soap and water 24 hours after treatment unless your healthcare provider instructs otherwise.
• You may wash Ycanth off your skin sooner if you develop severe blistering, severe pain, or other severe reactions. Do not use a washcloth, abrasive material, or vigorous rubbing because this could be painful.
• Contact your healthcare provider with any questions.

What should I avoid after receiving treatment with Ycanth?

• Avoid contact with treated areas of your skin, including mouth (oral contact).
• Avoid applying other products to treated areas until 24 hours after receiving treatment or until after washing Ycanth off treated areas of your skin.
• Ycanth is flammable, even after drying. Avoid fire, flame, or smoking near lesion(s) during and after treatment until Ycanth is washed off your skin.

Drug Interactions with Ycanth

No current information is available on potential drug interactions with Ycanth. Consult your doctor if you have any questions.

Pregnancy and Breastfeeding

Before receiving treatment with Ycanth, tell your healthcare provider if you:

• are pregnant or plan to become pregnant. It is not known if Ycanth can harm your unborn baby.
• are breastfeeding or plan to breastfeed. Your healthcare provider should avoid applying Ycanth to areas of your skin where your baby could come into contact with Ycanth and get it in their mouth or eyes.

Talk to your healthcare provider about breastfeeding while Ycanth is on your skin.

Summary

Ycanth is a prescription topical medication for molluscum contagiosum in adult and pediatric patients 2 years and older. Serious side effects if swallowed or comes into contact with mouth or eyes. Other serious side effects include eye contact reactions and skin reactions. Consult your doctor before using Ycanth if pregnant or breastfeeding.